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Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy

By replenishing glutathione and attenuating redox- and MMP-driven peripheral sensitizationwhile potentially modulating glutamatergic signalingNAC targets neuropathic and neuroinflammatory pathways that complement the GABAergic effects of topical clonazepam and the TRPV1 desensitization induced by capsaicin 14